The start of a new year is often the time when people re-affirm their commitments or set new goals for the upcoming months. It’s a fresh start and a time to tackle life with enthusiasm. It’s also a great time to kick your training, recruiting and fundraising into high gear! The holidays might be behind us, but the spirit of the giving season remains. People will be so excited to hear about your plans to commit 3 days in 2020!
When you’re reaching out to people for donations, or to ask them to walk with you, it will be totally natural that people have questions about the impact of the 3-Day.
Luckily, Susan G. Komen has created infographics that make it easy to answer these questions, and to learn more about the cause you are working so hard for. You can see the full range of infographics on the 3 Day website, or easily download some of the newest additions to make the most of your information-sharing. Print them to pass out, attach the files to your fundraising emails, or post the images on social media.
These are eye-catching and to-the-point breakdowns to motivate you, and those around you, to continue working and walking towards a cure.
These infographics give an overview of 3-Day fundraising overall, including the fact that we have raised more than $863 million since the 3-Day began in 2003! They also show the local impact that the 3-Day makes in states like Texas, California, Illinois, Massachusetts and many more.
This helps us fully understand the direct effect of our work, both in the states where we walk the 3-Day, and in other states as well! Komen released these easy infographics to show the true, real impact of local research dollars. These are also great informational resources to share with potential donors, or to send to your donors from your 2019 3-Day to show them just how much their support means. Because it means the world to many people!
These are perfect for donors who have more specific questions, for new team members, or to share on your first training walks of 2020.
If you want more information about Susan G. Komen and the 3-Day, you can ALWAYS reach out to your coach with questions, or check out the 3-Day website to find answers to Frequently Asked Questions, along with more information about the 3-Day experience.
This information is created for you, to make your life easier as you prepare for your 3-Day journey this year! We hope it inspires your steps and gets you moving in the right direction.
Dr. Zhang, can you tell us a bit about what led you to do breast cancer research?
My mother was diagnosed with ER+ Stage II breast cancer in 2012. She is still undergoing treatment and luckily everything looks fine now. But as a breast cancer researcher, I know she is still at risk of recurrence, just as many other breast cancer survivors. Therefore, curing breast cancer, specifically metastatic breast cancer, has become the major focus of my research. As a co-survivor, I am committed to providing better outcomes for breast cancer patients like my mother.
On The Route
Since we’ve got some time, could you tell us a bit about your current research?
Our research is focused on a single question: How we can harness the immune system to fight breast cancer? The immune system has the ability to kill tumor cells. However, tumors have learned to “hide” using help from cells that “turn off” the immune system (immunosuppressive cells) allowing the tumor to survive. In our work published in Nature Cell Biology we showed that targeting the immunosuppressive cells allows the immune system to do what it should be doing – killing tumor cells.
This approach will undoubtedly affect treatments relying on the immune system, including immunotherapies and some chemotherapies. We will continue to investigate how to target these immunosuppressive cells so that other therapies will work more efficiently. We will study how metastatic tumors differ from primary tumors in terms of recruitment of these immunosuppressive cells, helping us identify more effective strategies against metastatic breast cancer.
Now that we’ve made it “home” for the night and are enjoying the support of our crew, can you tell us how your work would be affected without Komen funding?
Komen research dollars were instrumental in establishing my work in immunotherapy. Komen not only funded our research, but also allowed me to assemble a team of senior scientists with the necessary expertise to advise us on the development of our research. This is tremendously important for a new lab to start in an unfamiliar field. I am very grateful and hope to continue to make contributions in this field to reward Komen’s support!
What is the potential impact of this research for breast cancer patients?
I believe this approach can improve the ability of the immune response to defend itself against the tumor. An immune system capable of attacking tumor cells could also be effective at killing any tumor cells that have returned (recurrence) or that have spread (metastasized). To enhance anti-tumor immunity would allow us to enhance the effectiveness of several other therapies. We are investigating several different ways of achieving this goal, and working on getting one of these approaches to the clinic as soon as possible.
Look at all of these enthusiastic supporters out along the route! Are you involved in any efforts related to cancer/breast cancer, outside of your lab?
Over the last four years, I have organized a breast cancer education program. The program invites breast cancer researchers at the Texas Medical Center (including Baylor College of Medicine, MD Anderson Cancer center and many other institutions) to a retreat where they present their research and receive feedback from faculty. The retreat also includes a nationally renowned keynote speaker every year.
To bring the patient voice to research, I have served as the Activity Director for the annual Metastatic Breast Cancer Conference. This nationwide conference provides a platform for patients, advocates, clinicians, and scientists to exchange ideas and discuss the most demanding needs and concerns for metastatic breast cancer patients.
The finish line is in sight! Can you tell us about a defining moment when you realized the impact our work has in the fight against breast cancer?
I am so proud of our team and that we have successfully established a research program and developed interdisciplinary expertise which can be quite the challenge. We have worked to know a lot about breast cancer cells themselves. Now we also know something about the “good” and “bad” immune cells that have made their way inside the tumors. The combination of this knowledge has greatly broadened our research scope and revealed several new opportunities. We have seen dramatic effects of the immune system on tumor progression. In some of our experiments, an unleashed immune system can sometimes completely eradicate an aggressive breast tumor. If this effect can also be realized in patients, it would vastly accelerate our progress of curing breast cancer.
Dr. Zhang and his mom at Yellowstone in 2013, one year after her diagnosis and surgery.
Thanks for walking us through your research, Dr. Zhang! Any final thoughts you’d like to share with our walkers, crew and supporters?
We are in the process of understanding how the rest of breast cancers resist or become resistant to current therapies. We believe we have some promising findings and hopefully in the near future we will be able to address this question for all patients.
As a co-survivor, I remember the side effects of my mother’s treatment. Conversations with advocates have opened my eyes to the real needs and hopes for patients, which should always be our top priority in pre-clinical research. These interactions help me gauge the importance of our findings and help us decide the right direction.
Dr. Xiang Zhang is an Assistant Professor at the Lester and Sue Smith Breast Center at Baylor College of Medicine. Since 1982, Susan G. Komen has funded $920 million in breast cancer research, second only to the U.S. government and more than any other nonprofit in the world. Learn more here.
Dr. Zhang meets with patient advocates Susan Rafte and Josh Newby at the Annual SABCS meeting.
Three things to know about Dr. Zhang:
My mom is excited that my research can reach a broader advocacy audience and would like to express her gratefulness to Komen.
Both of my maternal grandparents were biomedical scientists. I lived with them throughout my childhood due to my parents’ busy working schedules. They deeply influenced me and stimulated my interest in science. They also encouraged me to come to the US to pursue my science dream. They both passed away five years ago, but will be forever live in my heart.
Although my wife, Iris Zhang, is not a scientist, she has always been a fan of scientists. She attended my seminars whenever she could and helped me prepare my talks. She takes great care of our family while I work hard in the lab. Her support is instrumental to my research career!
The bond between sisters is truly unique and special, but the bond between “Titsters” is even deeper! Just ask Angela and Shelly, a sister duo who are part of the 3 Day family. Angela is currently battling breast cancer, and Shelly walks for Team Titster in the Twin Cities 3-Day in her honor.
From a young age, these two were joined at the hip, which meant Angela getting all her hair cut off when Shelly wanted to play “beauty parlor” or putting on plays and concerts together in their neighborhood. These “Titsters,” Angela’s childhood name for her sister, have been there for each other through it all.
That journey and support also includes Angela’s ongoing fight with breast cancer, one that Shelly has been a part of since Angela’s diagnosis. Angela was initially diagnosed with cancer when she was seven months pregnant, and her sister “was there immediately to ensure she was there for the birth of my baby girl and to hold my hand during my first chemotherapy. During that chemotherapy, all we did was laugh at videos, reminisce on memories, and I think about that more than being sick after the treatment.”
“After I completed my treatment after my first round of breast cancer, I went to a pretty dark place. The mental and physical struggle after treatment can be more challenging than anything. Woman and men feel more alone than ever. They have constant help, messages, and support during treatment, but what happens after is way more crucial. During treatment, we are in survival mode and cannot fully comprehend that we are going through cancer. Once treatment is done, the messages and help dwindle but the pain is still there. Our body is adjusting and still combatting the toll of chemotherapy, surgeries and radiation. Mentally, we never recover. The constant thought of recurrence always lingers and life is never the same. At the same time, we gain strength in a different way and look at the world and see that life is a gift. We cherish memories differently, we see the kindness of family and our community, and know that every day counts.”
Angela’s treatment will continue for the rest of her life, as she was diagnosed with Stage IV metastatic breast cancer in January of 2016. Stage IV research made up nearly 40% of Susan G. Komen’s overall research investment in 2016, with more than $166 million in funding for over 400 research grants and more than 40 clinical trials focused on metastatic disease to date. Aside from research and monetary support, Angela says she is constantly amazed by the support she receives from her family and even the community at large.
“What is so enlightening with all these clinical trials is that everything is so new at this point. And it is scary regardless, but what I like to tell people is that every day is a gift, but also a battle. Cancer is not going to control my life. It’s always going to be a part of me, but it does not define me.
“I’m also confident that I will live my life to inspire people and show people that despite being diagnosed with cancer, it doesn’t define you. I keep a happy journal, and at the end of every day I write my favorite part of the day, whether it’s a wonderful moment with my kids or a great conversation with my sister.”
Angela also credits Shelly as her rock, even from states away.
“The bond I have with my sister has helped me tremendously with this struggle and she truly showcases the bond that sisters have. She was there to comfort me and help me understand this it’s okay to still cry, but more importantly to laugh. We live in different states and I know that signing up for the 3-Day was just another way to show that she’s always there to face my battles with me, even if we cannot do it together.”
Part of Shelly’s support has come through her involvement in the 3-Day, which began as a crew member and has continued as a walker and fundraiser for the team she formed last year, Team Titster. Her first year on the 3-Day was a monumental one.
“When I signed up to be in the crew, part of the sign-up mentioned possibly being a part of the Opening or Closing Ceremony, speaking and carrying the sister flag,” Shelly explained when talking about speaking at her first walk. “The day before the walk at Crew Training, I met a bunch of very friendly, fun gals, who when I spoke on stage the next morning, cheered me on, even though I was nervous, and even though I was a stranger to them up until the day before. That has been my experience with everyone connected to the walk. Just good people.”
For her second year with the 3 Day, Shelly took to the trails and walked in her sister’s honor.
“When I decided to walk the next year, I was a little intimidated by the fundraising. But I found that when I reached out to my network to let them know why I was walking, and asked them to consider donating, people were more than willing to support me and Angie and the cause. I also found that almost every one of them had a connection to breast cancer. That alone is sad, but it motivated me even more to walk for those who also had loved ones battling or had battled the disease.”
Shelly helped her fundraising cause by casting a wide net for her initial email ask with a link to her page, along with a write up about Angela and a picture of “my little sister hero.” She also writes a 3-Day blog and shares that along with thank you cards to all her supporters to help them feel like they were there for her journey along the 60 miles.
When she started Team Titster in her third year on the 3-Day, Shelly expanded her fundraising email list and worked on her social media to raise even more. She targeted her competitive spirit and eventually raised more than $2,000 more than her first year. She was also the #7 Top Fundraiser for the Twin Cities 3-Day.
This success is no surprise to Angela, who has always been inspired and supported by their sisterhood.
“Shelly has always been my role model, and is someone that I’m inspired to be like. She is always the first person I want to talk to when I’m having a bad day, but more importantly, I want to talk to her in my great days.”
The love is certainly mutual, with Shelly calling Angela a super hero.
“Angie is small in stature but big in personality, perseverance and mostly in heart. She is feisty and fun, outgoing and stubborn, and those are all things we have in common. […] I realize that I have the best sister in the world. She doesn’t judge me, she’s been there for me when others have not been, and I am so proud of her in every way possible. Angie is my heart.”
That heart is going to finally experience the 3-Day for the first time this year. Angela will be making the trip from Chicago to the Twin Cities 3-Day in 2017 to cheer on Team Titster, which Shelly hopes to grow this year as well.
“I’m excited to be there the first time to cheer on my sister and Team Titster!” Angela enthuses. “I’m also happy to be able to volunteer and see the 3-Day. I’m thrilled and a bit nervous for the emotional experience but more importantly, I can’t wait to see and listen to the inspiring stories, and to hold the hands of Team Titster and fellow walkers.
“I know this walk means a lot to Shelly, and I know that every mile she walks, she truly is walking in my shoes to take some of the pain away. I’ve always looked up to my sister. She has more determination, heart and spirit than anyone I’ve ever met. I’ve also come to realize that those qualities are what inspires me to fight harder every day.”
Shelly echoes that determination, saying that the 3-Day is “emotional (lots of crying, both happy and heart wrenching), challenging (walking and training to walk 60 miles is no easy feat), and unforgettable (experiences and memories that are priceless and make you want to come back).”
Both Angela and Shelly will continue to come back as walkers, volunteers or supporters, until a cure is found.
“There is still no cure for breast cancer,” Shelly states simply. “That in itself gives me purpose and determination to keep doing the walks. My favorite button on my 3-Day water pack is ‘Every Blister Saves a Sister.’ I am prone to blisters, no matter how much training I do, (last year, I had 11 by the end of Day 3) so walking until there is a cure is something I feel like I can do, and will try to keep doing until there is no more breast cancer. Blisters do not hurt, physically or emotionally, as much as cancer does. And of course, my sister inspires me, not just to do the walk, but she inspires me every day.”
The power of sisterhood on the 3-Day is real, and every step makes a difference.